Under-reporting of Adverse Events in the Biomedical Literature
Ronald N. Kostoff; Ronald N. Kostoff (E-mail:ronald.kostoff@pubpolicy.gatech.edu)
2016-11-03
Source PublicationJournal of Data and Information Science
Volume1Issue:4Pages:10-32
Abstract
Purpose: To address the under-reporting of research results, with emphasis on the underreporting/distorted reporting of adverse events in the biomedical research literature.
Design/methodology/approach: A four-step approach is used:(1) To identify the characteristics of literature that make it adequate to support policy; (2) to show how each of these characteristics becomes degraded to make inadequate literature; (3) to identify incentives to prevent inadequate literature; and (4) to show policy implications of inadequate literature.
Findings: This review has provided reasons for, and examples of, adverse health effects of myriad substances (1) being under-reported in the premiere biomedical literature, or (2) entering this literature in distorted form. Since there is no way to gauge the extent of this under/distorted-reporting, the quality and credibility of the‘premiere’biomedical literature is unknown. Therefore, any types of meta-analyses or scientometric analyses of this literature will have unknown quality and credibility. The most sophisticated scientometric analysis cannot compensate for a highly flawed database.
Research limitations: The main limitation is in identifying examples of under-reporting. There are many incentives for under-reporting and few dis-incentives.
Practical implications: Almost all research publications, addressing causes of disease, treatments for disease, diagnoses for disease, scientometrics of disease and health issues, and other aspects of healthcare, build upon previous healthcare-related research published. Many researchers will not have laboratories or other capabilities to replicate or validate the published research, and depend almost completely on the integrity of this literature. If the literature is distorted, then future research can be misguided, and health policy recommendations can be ineffective or worse.
Originality/value: This review has examined a much wider range of technical and nontechnical causes for under-reporting of adverse events in the biomedical literature than previous studies.
; Purpose: To address the under-reporting of research results, with emphasis on the underreporting/distorted reporting of adverse events in the biomedical research literature.
Design/methodology/approach: A four-step approach is used:(1) To identify the characteristics of literature that make it adequate to support policy; (2) to show how each of these characteristics becomes degraded to make inadequate literature; (3) to identify incentives to prevent inadequate literature; and (4) to show policy implications of inadequate literature.
Findings: This review has provided reasons for, and examples of, adverse health effects of myriad substances (1) being under-reported in the premiere biomedical literature, or (2) entering this literature in distorted form. Since there is no way to gauge the extent of this under/distorted-reporting, the quality and credibility of the‘premiere’biomedical literature is unknown. Therefore, any types of meta-analyses or scientometric analyses of this literature will have unknown quality and credibility. The most sophisticated scientometric analysis cannot compensate for a highly flawed database.
Research limitations: The main limitation is in identifying examples of under-reporting. There are many incentives for under-reporting and few dis-incentives.
Practical implications: Almost all research publications, addressing causes of disease, treatments for disease, diagnoses for disease, scientometrics of disease and health issues, and other aspects of healthcare, build upon previous healthcare-related research published. Many researchers will not have laboratories or other capabilities to replicate or validate the published research, and depend almost completely on the integrity of this literature. If the literature is distorted, then future research can be misguided, and health policy recommendations can be ineffective or worse.
Originality/value: This review has examined a much wider range of technical and nontechnical causes for under-reporting of adverse events in the biomedical literature than previous studies.
SubtypeExpert Reviews
KeywordUnder-reporting Publication Bias Reporting Bias Manufactured Research Research Misconduct Research Malfeasance Biomedical Literature
Subject Area新闻学与传播学 ; 图书馆、情报与文献学
DOI10.20309/jdis.201623
URL查看原文
Indexed By其他
Language英语
Citation statistics
Document Type期刊论文
Identifierhttp://ir.las.ac.cn/handle/12502/8905
CollectionJournal of Data and Information Science_Journal of Data and Information Science-2016
Corresponding AuthorRonald N. Kostoff (E-mail:ronald.kostoff@pubpolicy.gatech.edu)
AffiliationSchool of Public Policy, Georgia Institute of Technology, Gainesville, VA 20155, USA
Recommended Citation
GB/T 7714
Ronald N. Kostoff,Ronald N. Kostoff . Under-reporting of Adverse Events in the Biomedical Literature[J]. Journal of Data and Information Science,2016,1(4):10-32.
APA Ronald N. Kostoff,&Ronald N. Kostoff .(2016).Under-reporting of Adverse Events in the Biomedical Literature.Journal of Data and Information Science,1(4),10-32.
MLA Ronald N. Kostoff,et al."Under-reporting of Adverse Events in the Biomedical Literature".Journal of Data and Information Science 1.4(2016):10-32.
Files in This Item: Download All
File Name/Size DocType Version Access License
20160402.pdf(2176KB)期刊论文作者接受稿开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Ronald N. Kostoff]'s Articles
[Ronald N. Kostoff (E-mail:ronald.kostoff@pubpolicy.gatech.edu)]'s Articles
Baidu academic
Similar articles in Baidu academic
[Ronald N. Kostoff]'s Articles
[Ronald N. Kostoff (E-mail:ronald.kostoff@pubpolicy.gatech.edu)]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Ronald N. Kostoff]'s Articles
[Ronald N. Kostoff (E-mail:ronald.kostoff@pubpolicy.gatech.edu)]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: 20160402.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.